The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135876: Hydroxyindole O-methyltransferase-like protein

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetylserotonin O-methyltransferase. [EC: 2.1.1.4]
S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin.
  • Some other hydroxyindoles also act as acceptor, more slowly.
24 A0A0K1H566 A0A0K1H566 A0A191B549 A0A191B549 A0A1B5A3U0 A0A1B5A3U0 B3GSH5 B3GSH5 D2KCH8 D2KCH8
(14 more...)
Demethylspheroidene O-methyltransferase. [EC: 2.1.1.210]
S-adenosyl-L-methionine + demethylspheroidene = S-adenosyl-L-homocysteine + spheroidene.
  • In Rhodopseudomonas capsulata and Rubrivivax gelatinosus the enzyme is involved in biosynthesis of spheroidene.
  • In Rubrivivax gelatinosus the enzyme also catalyzes the methylation of demethylspirilloxanthin to spirilloxanthin and the methylation of 3,4-didehydrorhodopin to anhydrorhodovibrin.
4 A0A0E2PXY0 A0A0E2PXY0 D5AP78 D5AP78