The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135816: 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (uracil(747)-C(5))-methyltransferase. [EC: 2.1.1.189]
S-adenosyl-L-methionine + uracil(747) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methyluracil(747) in 23S rRNA.
  • The enzyme specifically methylates uracil(747) at C(5) in 23S rRNA.
2164 A0A011MKM3 A0A011MKM3 A0A014PSC4 A0A014PSC4 A0A017IJJ2 A0A017IJJ2 A0A017QF02 A0A017QF02 A0A022PJI8 A0A022PJI8
(2154 more...)
TRNA (uracil(54)-C(5))-methyltransferase. [EC: 2.1.1.35]
S-adenosyl-L-methionine + uracil(54) in tRNA = S-adenosyl-L-homocysteine + 5-methyluracil(54) in tRNA.
  • Unlike this enzyme, EC 2.1.1.74 uses 5,10-methylenetetrahydrofolate and FADH(2) to supply the atoms for methylation of U54.
16 A0A0S1XEE9 A0A0S1XEE9 A0A0X9HJQ8 A0A0X9HJQ8 A0A160VTD0 A0A160VTD0 A0A1F1TH82 A0A1F1TH82 I6V1L9 I6V1L9
(6 more...)