The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135509: Ribosomal RNA-processing protein 8

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
6 A8XI07 (/ISS) O44410 (/ISS) Q54CP1 (/ISS) Q5U4F0 (/ISS) Q84JC0 (/ISS) Q9DB85 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 O43159 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9DB85 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O43159 (/IPI)
S-adenosylmethionine-dependent methyltransferase activity GO:0008757
Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
1 O43159 (/TAS)
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
1 O43159 (/IDA)
Methylated histone binding GO:0035064
Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
1 Q9DB85 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
6 A8XI07 (/ISS) O44410 (/ISS) Q54CP1 (/ISS) Q5U4F0 (/ISS) Q84JC0 (/ISS) Q9DB85 (/ISS)
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
1 O43159 (/IDA)
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
1 Q9DB85 (/ISO)
Chromatin silencing at rDNA GO:0000183
Repression of transcription of ribosomal DNA by altering the structure of chromatin.
1 O43159 (/TAS)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
1 O43159 (/IMP)
Cellular response to glucose starvation GO:0042149
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
1 Q9DB85 (/ISO)
Regulation of transcription by glucose GO:0046015
Any process involving glucose that modulates the frequency, rate or extent or transcription.
1 O43159 (/IMP)
Regulation of transcription by glucose GO:0046015
Any process involving glucose that modulates the frequency, rate or extent or transcription.
1 Q9DB85 (/ISO)
Positive regulation of cell cycle arrest GO:0071158
Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
1 O43159 (/IMP)
Positive regulation of cell cycle arrest GO:0071158
Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
1 Q9DB85 (/ISO)
Intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
1 O43159 (/IMP)
Intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332
A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
1 Q9DB85 (/ISO)

There are 16 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromatin silencing complex GO:0005677
Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
6 A8XI07 (/ISS) O44410 (/ISS) Q54CP1 (/ISS) Q5U4F0 (/ISS) Q84JC0 (/ISS) Q9DB85 (/ISS)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
6 A8XI07 (/ISS) O44410 (/ISS) Q54CP1 (/ISS) Q5U4F0 (/ISS) Q84JC0 (/ISS) Q9DB85 (/ISS)
RDNA heterochromatin GO:0033553
A region of heterochromatin located at the rDNA repeats in a chromosome.
6 A8XI07 (/ISS) O44410 (/ISS) Q54CP1 (/ISS) Q5U4F0 (/ISS) Q84JC0 (/ISS) Q9DB85 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 O43159 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9DB85 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 O43159 (/TAS)
Chromatin silencing complex GO:0005677
Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
1 O43159 (/IDA)
Chromatin silencing complex GO:0005677
Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
1 Q9DB85 (/ISO)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 O43159 (/IDA)
Nucleolus GO:0005730
A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
1 Q9DB85 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 O43159 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9DB85 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 O43159 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9DB85 (/ISO)
RDNA heterochromatin GO:0033553
A region of heterochromatin located at the rDNA repeats in a chromosome.
1 O43159 (/IDA)
RDNA heterochromatin GO:0033553
A region of heterochromatin located at the rDNA repeats in a chromosome.
1 Q9DB85 (/ISO)