The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135480: Ribosomal RNA small subunit methyltransferase H

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
16S rRNA (cytosine(1402)-N(4))-methyltransferase. [EC: 2.1.1.199]
S-adenosyl-L-methionine + cytosine(1402) in 16S rRNA = S-adenosyl-L- homocysteine + N(4)-methylcytosine(1402) in 16S rRNA.
  • RsmH catalyzes the N(4)-methylation of cytosine(1402) and RsmI (EC 2.1.1.198) catalyzes the 2'-O-methylation of cytosine(1402) in 16S rRNA.
  • Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
50 A0A059IWB9 A0A060Q473 A0A098AR84 A0A098EF44 A0A0A1XYJ5 A0A0C7D8Z9 A0A0F3N7W8 A0A0F3NC78 A0A0F3NFM6 A0A0F3NPP7
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