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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135475: Malonyl-[acyl-carrier protein] O-methyltransferase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Malonyl-[acyl-carrier protein] O-methyltransferase. [EC: 2.1.1.197]
S-adenosyl-L-methionine + malonyl-[acyl-carrier protein] = S-adenosyl-L- homocysteine + malonyl-[acyl-carrier protein] methyl ester.
  • Involved in an early step of biotin biosynthesis in Gram-negative bacteria.
  • This enzyme catalyzes the transfer of a methyl group to the omega- carboxyl group of malonyl-[acyl-carrier protein] forming a methyl ester.
  • The methyl ester is recognized by the fatty acid synthetic enzymes, which process it via the fatty acid elongation cycle to give pimelyl- [acyl-carrier-protein] methyl ester.
  • While the enzyme can also accept malonyl-CoA, it has a much higher activity with malonyl-[acyl-carrier protein].
 80 A0A023NY82 A0A066ZS32 A0A075K1W2 A0A090AH42 A0A0A0ERF8 A0A0A0ESE0 A0A0A6NYD4 A0A0A6P685 A0A0B7IT32 A0A0C3NRP8
(70 more...)
Thiol oxidase. [EC: 1.8.3.2]
2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2).
  • R may be =S or =O, or a variety of other groups.
  • The enzyme is not specific for R'.
 3 A0A077YX42 A0A085M2I4 A0A085N8G2
Carboxylesterase. [EC: 3.1.1.1]
A carboxylic ester + H(2)O = an alcohol + a carboxylate.
  • Wide specificity; also hydrolyzes vitamin A esters.
  • The enzymes from microsomes also catalyze the reactions of EC 3.1.1.2, EC 3.1.1.5, EC 3.1.1.6, EC 3.1.1.23, EC 3.1.1.28, EC 3.1.2.2, EC 3.5.1.4, and EC 3.5.1.13.
  • Formerly EC 3.1.1.12.
 1 Q21FY5