The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 135322: Ribosomal RNA large subunit methyltransferase I

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
23S rRNA (cytosine(1962)-C(5))-methyltransferase. [EC: 2.1.1.191]
S-adenosyl-L-methionine + cytosine(1962) in 23S rRNA = S-adenosyl-L- homocysteine + 5-methylcytosine(1962) in 23S rRNA.
  • The enzyme specifically methylates cytosine(1962) at C(5) in 23S rRNA.
2122 A0A010P5F1 A0A010P5F1 A0A011MZH7 A0A011MZH7 A0A011P662 A0A011P662 A0A011P6G7 A0A011P6G7 A0A011PHW6 A0A011PHW6
(2112 more...)
Acetylserotonin O-methyltransferase. [EC: 2.1.1.4]
S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin.
  • Some other hydroxyindoles also act as acceptor, more slowly.
8 C9Y7F8 C9Y7F8 G0EU18 G0EU18 Q0KEW6 Q0KEW6 R7X9G7 R7X9G7