CATH Superfamily 3.40.50.150

FunFam 135099: Ribosomal RNA large subunit methyltransferase K/L

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term	Annotations	Evidence
23S rRNA (guanine(2445)-N(2))-methyltransferase. [EC: 2.1.1.173] S-adenosyl-L-methionine + guanine(2445) in 23S rRNA = S-adenosyl-L- homocysteine + N(2)-methylguanine(2445) in 23S rRNA. The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine(2445) at N(2) in 23S rRNA. Formerly EC 2.1.1.52.	61	A0A009GGL6 A0A009I0J7 A0A009JL39 A0A009QEI3 A0A009RVY7 A0A009SC43 A0A010KR42 A0A014AWA3 A0A014BHR2 A0A014CHK0 (51 more...)
23S rRNA (guanine(2069)-N(7))-methyltransferase. [EC: 2.1.1.264] S-adenosyl-L-methionine + guanine(2069) in 23S rRNA = S-adenosyl-L- homocysteine + N(7)-methylguanine(2069) in 23S rRNA. The enzyme specifically methylates guanine(2069) at position N7 in 23S rRNA. In gamma-proteobacteria the enzyme also catalyzes EC 2.1.1.173, while in beta-proteobacteria the activities are carried out by separate proteins. The enzyme from the gamma-proteobacterium Escherichia coli has RNA unwinding activity as well.	61	A0A009GGL6 A0A009I0J7 A0A009JL39 A0A009QEI3 A0A009RVY7 A0A009SC43 A0A010KR42 A0A014AWA3 A0A014BHR2 A0A014CHK0 (51 more...)

CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

Functional Families

FunFam 135099: Ribosomal RNA large subunit methyltransferase K/L

There are 2 EC terms in this cluster