The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 132883: Genome polyprotein

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 P06935 (/IPI) P14340 (/IPI) P29991 (/IPI) Q9E7P0 (/IPI)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P06935 (/IMP)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 P06935 (/IMP)
RNA-directed 5'-3' RNA polymerase activity GO:0003968
Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
1 Q8B489 (/IMP)
Peptidase activity GO:0008233
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
1 P06935 (/IDA)
RNA strand annealing activity GO:0033592
Facilitates the base-pairing of complementary single-stranded RNA.
1 P06935 (/IMP)
DNA/DNA annealing activity GO:1990814
A nucleic acid binding activity that brings together complementary sequences of ssDNA so that they pair by hydrogen bonds to form a double-stranded DNA.
1 P06935 (/IMP)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Viral budding from ER membrane GO:0046762
A viral budding that starts with formation of a membrane curvature in the host ER membrane.
2 P03314 (/IDA) P17763 (/IDA)
Suppression by virus of host apoptotic process GO:0019050
Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.
1 P06935 (/IDA)
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
1 G4XII4 (/IDA)
Viral genome replication GO:0019079
Any process involved directly in viral genome replication, including viral nucleotide metabolism.
1 G4XII4 (/IMP)
Evasion or tolerance by virus of host immune response GO:0030683
Any process, either active or passive, by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q2YHF0 (/IMP)
RNA stabilization GO:0043489
Prevention of degradation of RNA molecules.
1 P06935 (/IMP)
Positive regulation of viral genome replication GO:0045070
Any process that activates or increases the frequency, rate or extent of viral genome replication.
1 P06935 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytoplasmic viral factory GO:0039714
A viral factory located in the cytoplasm of a host cell.
2 P06935 (/IDA) P17763 (/IDA)
Viral envelope GO:0019031
The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.
1 P03314 (/IMP)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
1 P06935 (/IMP)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 P06935 (/IMP)