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CATH Superfamily 3.40.50.150

Vaccinia Virus protein VP39

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Vaccinia Virus protein VP39
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 131377: DNA methyltransferase PMT1-like protein

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
TRNA (cytosine(38)-C(5))-methyltransferase. [EC: 2.1.1.204]
S-adenosyl-L-methionine + cytosine(38) in tRNA = S-adenosyl-L- homocysteine + 5-methylcytosine(38) in tRNA.
  • The eukaryotic enzyme catalyzes methylation of cytosine(38) in the anti-codon loop of tRNA(Asp)(GTC), tRNA(Val)(AAC) and tRNA(Gly)(GCC).
  • Methylation by Dnmt2 protects tRNAs against stress-induced cleavage by ribonuclease.
  • Formerly EC 2.1.1.29.
 6 O14717 O55055 Q4G073 Q5I0V6 Q6ICS7 Q7YS61
DNA (cytosine-5-)-methyltransferase. [EC: 2.1.1.37]
S-adenosyl-L-methionine + DNA = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
  • Formerly EC 2.1.1.73.
 6 A0A075B350 A0A0B2RNV8 A0A132AC86 D7G6U6 F4NTW9 G4VIU7
Glycylpeptide N-tetradecanoyltransferase. [EC: 2.3.1.97]
Tetradecanoyl-CoA + glycylpeptide = CoA + N-tetradecanoylglycylpeptide.
  • The enzyme from Saccharomyces cerevisiae is highly specific for tetradecanoyl-CoA, and for N-terminal glycine in oligopeptides containing serine in the 5-position.
  • The enzyme from mammalian heart transfers acyl groups to a specific acceptor protein of 51 kDa.
 3 B7QI83 B9RP83 E0W2G1
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