The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphoglycerate mutase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13285: Inositol hexakisphosphate and diphosphoinositol-pe...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 20 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inositol-1,3,4,5,6-pentakisphosphate kinase activity GO:0000827
Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.
10 A2ARP1 (/ISS) A7Z050 (/ISS) O43314 (/ISS) P0C644 (/ISS) P91309 (/ISS) Q5RDF1 (/ISS) Q5REW0 (/ISS) Q5XHF8 (/ISS) Q6ZQB6 (/ISS) Q9VR59 (/ISS)
Inositol hexakisphosphate 5-kinase activity GO:0000832
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.
10 A2ARP1 (/ISS) A7Z050 (/ISS) O43314 (/ISS) P0C644 (/ISS) P91309 (/ISS) Q5RDF1 (/ISS) Q5REW0 (/ISS) Q5XHF8 (/ISS) Q6ZQB6 (/ISS) Q9VR59 (/ISS)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
10 A2ARP1 (/ISS) A7Z050 (/ISS) P0C644 (/ISS) P91309 (/ISS) Q5RDF1 (/ISS) Q5REW0 (/ISS) Q5XHF8 (/ISS) Q6PFW1 (/ISS) Q6ZQB6 (/ISS) Q9VR59 (/ISS)
Diphosphoinositol-pentakisphosphate kinase activity GO:0033857
Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.
10 A2ARP1 (/ISS) A7Z050 (/ISS) O43314 (/ISS) P0C644 (/ISS) P91309 (/ISS) Q5RDF1 (/ISS) Q5REW0 (/ISS) Q5XHF8 (/ISS) Q6ZQB6 (/ISS) Q9VR59 (/ISS)
Inositol hexakisphosphate kinase activity GO:0000828
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
3 O43314 (/IDA) Q6PFW1 (/IDA) Q6ZQB6 (/IDA)
Inositol hexakisphosphate kinase activity GO:0000828
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
3 F4J8C6 (/IGI) F4J8C7 (/IGI) Q84WW3 (/IGI)
Inositol heptakisphosphate kinase activity GO:0000829
Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
3 F4J8C6 (/IMP) F4J8C7 (/IMP) Q84WW3 (/IMP)
Diphosphoinositol-pentakisphosphate kinase activity GO:0033857
Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.
3 O43314 (/IDA) Q6PFW1 (/IDA) Q6ZQB6 (/IDA)
Inositol hexakisphosphate kinase activity GO:0000828
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
2 F4J8C6 (/IMP) F4J8C7 (/IMP)
Inositol hexakisphosphate kinase activity GO:0000828
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
2 A2ARP1 (/ISO) Q6ZQB6 (/ISO)
Inositol hexakisphosphate kinase activity GO:0000828
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
2 O43314 (/TAS) Q6PFW1 (/TAS)
Inositol heptakisphosphate kinase activity GO:0000829
Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
2 O43314 (/TAS) Q6PFW1 (/TAS)
Diphosphoinositol-pentakisphosphate kinase activity GO:0033857
Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.
2 F4J8C6 (/IMP) Q84WW3 (/IMP)
Diphosphoinositol-pentakisphosphate kinase activity GO:0033857
Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.
2 A2ARP1 (/ISO) Q6ZQB6 (/ISO)
Inositol-1,3,4,5,6-pentakisphosphate kinase activity GO:0000827
Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.
1 Q6PFW1 (/IDA)
Inositol-1,3,4,5,6-pentakisphosphate kinase activity GO:0000827
Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.
1 A2ARP1 (/ISO)
Inositol hexakisphosphate 5-kinase activity GO:0000832
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.
1 Q6PFW1 (/IDA)
Inositol hexakisphosphate 5-kinase activity GO:0000832
Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.
1 A2ARP1 (/ISO)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 O43314 (/IDA)
ATP binding GO:0005524
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
1 Q6ZQB6 (/ISO)

There are 12 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Inositol metabolic process GO:0006020
The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
10 A2ARP1 (/ISS) A7Z050 (/ISS) O43314 (/ISS) P0C644 (/ISS) P91309 (/ISS) Q5RDF1 (/ISS) Q5REW0 (/ISS) Q5XHF8 (/ISS) Q6ZQB6 (/ISS) Q9VR59 (/ISS)
Inositol phosphate biosynthetic process GO:0032958
The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
3 F4J8C6 (/IMP) F4J8C7 (/IMP) Q84WW3 (/IMP)
Inositol metabolic process GO:0006020
The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
2 F4J8C6 (/IMP) Q84WW3 (/IMP)
Defense response to fungus, incompatible interaction GO:0009817
A response of an organism to a fungus that prevents the occurrence or spread of disease.
2 F4J8C6 (/IMP) F4J8C7 (/IMP)
Jasmonic acid and ethylene-dependent systemic resistance GO:0009861
The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
2 F4J8C6 (/IMP) F4J8C7 (/IMP)
Inositol phosphate metabolic process GO:0043647
The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
2 O43314 (/TAS) Q6PFW1 (/TAS)
Inositol metabolic process GO:0006020
The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
1 Q6PFW1 (/IDA)
Inositol metabolic process GO:0006020
The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
1 A2ARP1 (/ISO)
Positive regulation of defense response to insect GO:1900367
Any process that activates or increases the frequency, rate or extent of defense response to insect.
1 F4J8C6 (/IMP)
Positive regulation of vitamin E biosynthetic process GO:1904966
Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.
1 F4J8C6 (/IMP)
Positive regulation of vitamin E biosynthetic process GO:1904966
Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.
1 Q84WW3 (/ISS)
Positive regulation of antifungal innate immune response GO:1905036
Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response.
1 F4J8C6 (/IMP)

There are 9 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
10 A2ARP1 (/ISS) A7Z050 (/ISS) O43314 (/ISS) P0C644 (/ISS) P91309 (/ISS) Q5RDF1 (/ISS) Q5REW0 (/ISS) Q5XHF8 (/ISS) Q6ZQB6 (/ISS) Q9VR59 (/ISS)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 B7WPL9 (/IDA) F8W9A8 (/IDA) O43314 (/IDA) Q6PFW1 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 B7WPL9 (/IDA) F8W9A8 (/IDA) Q6PFW1 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 A2ARP1 (/ISO) Q6ZQB6 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 O43314 (/TAS) Q6PFW1 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
2 F4J8C6 (/IDA) F4J8C7 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 A2ARP1 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P91309 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q84WW3 (/ISS)