The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
TPP-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 13202: Pyruvate decarboxylase isozyme 1

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Pyruvate decarboxylase. [EC: 4.1.1.1]
A 2-oxo acid = an aldehyde + CO(2).
  • Also catalyzes acyloin formation.
88 A0A060TB88 A0A060TB88 A0A084G8D6 A0A084G8D6 A0A0B7F7J8 A0A0B7F7J8 A0A0F4YPV3 A0A0F4YPV3 A0A0F8D0K2 A0A0F8D0K2
(78 more...)
Indolepyruvate decarboxylase. [EC: 4.1.1.74]
3-(indol-3-yl)pyruvate = 2-(indol-3-yl)acetaldehyde + CO(2).
  • More specific than EC 4.1.1.1.
14 A0A0L8VLD5 A0A0L8VLD5 A7A0U9 A7A0U9 B3LT15 B3LT15 E7KFE4 E7KFE4 E7LXD6 E7LXD6
(4 more...)
Phenylpyruvate decarboxylase. [EC: 4.1.1.43]
Phenylpyruvate = phenylacetaldehyde + CO(2).
  • Also acts on (indol-3-yl)pyruvate.
14 A0A0L8VLD5 A0A0L8VLD5 A7A0U9 A7A0U9 B3LT15 B3LT15 E7KFE4 E7KFE4 E7LXD6 E7LXD6
(4 more...)
Thiol oxidase. [EC: 1.8.3.2]
2 R'C(R)SH + O(2) = R'C(R)S-S(R)CR' + H(2)O(2).
  • R may be =S or =O, or a variety of other groups.
  • The enzyme is not specific for R'.
6 A0A0G4L7I7 A0A0G4L7I7 A0A0G4LVP3 A0A0G4LVP3 G0SB10 G0SB10
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