View in Gene3D

CATH Superfamily 3.40.50.1220

TPP-binding domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
TPP-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 13146: Probable 2-hydroxyacyl-CoA lyase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Oxalyl-CoA decarboxylase. [EC: 4.1.1.8]
Oxalyl-CoA = formyl-CoA + CO(2).
    		 510 A0A022GFT8 A0A023Z0Q6 A0A024KYA0 A0A025CWH4 A0A026RLB7 A0A026UMI9 A0A027TYT6 A0A028AST1 A0A028ED96 A0A029HTY6
    (500 more...)
    Benzoin aldolase. [EC: 4.1.2.38]
    Benzoin = 2 benzaldehyde.
      		 2 A0A174BGS6 D2Q6H6
      Acetolactate synthase. [EC: 2.2.1.6]
      2 pyruvate = 2-acetolactate + CO(2).
      • The reaction shown is in the pathway of biosynthesis of valine.
      • The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.
      • Formerly EC 4.1.3.18.
      		 1 A0A0T9TJ03
      CATH-Gene3D is a Global Biodata Core Resource Learn more...