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CATH Superfamily 3.40.50.1170

L-asparaginase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
L-asparaginase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1501: Cytoplasmic L-asparaginase I

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Asparaginase. [EC: 3.5.1.1]
L-asparagine + H(2)O = L-aspartate + NH(3).
    		 988 A0A014N365 A0A017IHG5 A0A022PFK1 A0A023E1P0 A0A023VC93 A0A023YXY8 A0A024L1W1 A0A025CNB4 A0A026RGI3 A0A026UH51
    (978 more...)
    1-alkyl-2-acetylglycerophosphocholine esterase. [EC: 3.1.1.47]
    1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + H(2)O = 1-alkyl- sn-glycero-3-phosphocholine + acetate.
      		 20 A0A085U8L8 A0A099KTG0 A0A099KU49 A0A099LH00 A0A0E8XJ25 A0A0H3B4U4 A0A0U1ELG4 A0A0U1QWI5 A0A161WSE9 A0JNU3
      (10 more...)
      Lysophospholipase. [EC: 3.1.1.5]
      2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate.
        		 5 A0JNU3 A8FVP8 C7RBC6 O88202 Q86U10
        Protein kinase C. [EC: 2.7.11.13]
        ATP + a protein = ADP + a phosphoprotein.
        • A family of serine- and threonine-specific protein kinases that depend on lipids for activity.
        • They can be activated by calcium but have a requirement for the second messenger diacylglycerol.
        • Members of this group of enzymes phosphorylate a wide variety of protein targets and are known to be involved in diverse cell- signaling pathways.
        • Members of the protein kinase C family also serve as major receptors for phorbol esters, a class of tumor promoters.
        • Formerly EC 2.7.1.37.
        		 1 A0A132A0L3