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CATH Superfamily 3.40.50.1100

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 25356: CBS-1, isoform a

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cysteine synthase. [EC: 2.5.1.47]
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
  • Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors.
  • Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53.
  • Formerly EC 4.2.99.8.
 1 Q9YBL2
O-phosphoserine sulfhydrylase. [EC: 2.5.1.65]
O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.
  • The enzyme from Aeropyrum pernix acts on both O-phospho-L-serine and O(3)-acetyl-L-serine, in contrast with EC 2.5.1.47, which acts only on O(3)-acetyl-L-serine.
 1 Q9YBL2
Cystathionine beta-synthase. [EC: 4.2.1.22]
L-serine + L-homocysteine = L-cystathionine + H(2)O.
  • A multifunctional enzyme: catalyzes beta-replacement reaction between L-serine, L-cysteine, cysteine thioethers or some other beta- substituted alpha-L-amino acids and a variety of mercaptans.
  • Formerly EC 4.2.1.21.
 1 Q9YBL2
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