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CATH Superfamily 3.40.50.10320

LmbE-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
LmbE-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1990: Putative N-acetylglucosaminylphosphatidylinositol ...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase. [EC: 3.5.1.103]
1-O-(2-acetamido-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + H(2)O = 1-O-(2-amino-2-deoxy-alpha-D-glucopyranosyl)-1D-myo-inositol + acetate.
  • This enzyme is considered the key enzyme and rate limiting step in the mycothiol biosynthesis pathway.
  • In addition to acetylase activity, the enzyme possesses weak mycothiol conjugate amidase activity, and shares sequence similarity with mycothiol S-conjugate amidase.
  • Formerly EC 3.1.1.n1.
 28 A0A063X9U9 A0A0D5CVY4 A0A0D7XS66 A0A0E1LNQ3 A0A0K6K002 A0A0K6K329 A0A0K6M1A1 A0A0M0L3B9 A0A0T8PX00 A0A0U0DI37
(18 more...)
N-acetylglucosaminylphosphatidylinositol deacetylase. [EC: 3.5.1.89]
6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + H(2)O = 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol + acetate.
  • Involved in the second step of glycosylphosphatidylinositol (GPI) anchor formation in all eukaryotes.
  • The enzyme appears to be composed of a single subunit (PIG-L in mammalian cells and GPI12 in Saccharomyces cerevisiae).
  • In some species, the long-chain sn-1-acyl group of the phosphatidyl group is replaced by a long-chain alkyl or alk-1-enyl group.
  • Formerly EC 3.1.1.69.
 1 I2C6H0