The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 52628: 3-ketoacyl-CoA thiolase Acetyl-CoA acetyltransfera...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetyl-CoA C-acetyltransferase. [EC: 2.3.1.9]
2 acetyl-CoA = CoA + acetoacetyl-CoA.
    514 A0A022LEW7 A0A022LP79 A0A023PBN2 A0A024C0G5 A0A031HIX7 A0A060B9L0 A0A062WUU1 A0A063CLR2 A0A063YZQ7 A0A066RJX7
    (504 more...)
    Acetyl-CoA C-acyltransferase. [EC: 2.3.1.16]
    Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
      117 A0A023PBN2 A0A076VZ09 A0A084J3M4 A0A0A8X0A8 A0A0B5QUY7 A0A0B6A3Z1 A0A0D0HYD6 A0A0D6RXX2 A0A0D6SPW4 A0A0D7D9W7
      (107 more...)
      3-oxoadipyl-CoA thiolase. [EC: 2.3.1.174]
      Succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.
      • The enzyme from the bacterium Escherichia coli also has the activity of EC 2.3.1.223.
      5 A0A010LLX5 A0A062KNS3 A0A062LZU6 F2JV90 J7LZ85
      Hydroxymethylglutaryl-CoA reductase. [EC: 1.1.1.88]
      (R)-mevalonate + CoA + 2 NAD(+) = 3-hydroxy-3-methylglutaryl-CoA + 2 NADH.
        1 F0ENN3
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