The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.
FunFam 52289: Polyketide synthase type I
There are 6 EC terms in this cluster
Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
EC Term | Annotations | Evidence |
---|---|---|
6-deoxyerythronolide-B synthase.
[EC: 2.3.1.94]
Propanoyl-CoA + 6 (2S)-methylmalonyl-CoA + 6 NADPH = 6-deoxyerythronolide B + 7 CoA + 6 CO(2) + H(2)O + 6 NADP(+).
|
9 | A0A0N1GUD6 A0A0N1NNV2 A0A0U1B824 A0A139Y074 A0A169PK31 G0Q182 K9UXZ1 S8F5N9 V5BCV6 |
Beta-ketoacyl-[acyl-carrier-protein] synthase I.
[EC: 2.3.1.41]
Acyl-[acyl-carrier-protein] + malonyl-[acyl-carrier-protein] = 3-oxoacyl- [acyl-carrier-protein] + CO(2) + [acyl-carrier-protein].
|
7 | A0A0M7F021 A0A0T9XEH0 A0A0U1AK83 A0A0U1ARP9 A0A0U1AU86 A0A1B6B292 A0A1N5S934 |
Mycocerosate synthase.
[EC: 2.3.1.111]
(1) A long-chain acyl-CoA + 3 methylmalonyl-CoA + 6 NADPH + a holo- [mycocerosate synthase] = a trimethylated-mycocerosoyl-[mycocerosate synthase] + 4 CoA + 3 CO(2) + 6 NADP(+) + 3 H(2)O. (2) A long-chain acyl-CoA + 4 methylmalonyl-CoA + 8 NADPH + a holo- [mycocerosate synthase] synthase = a tetramethylated-mycocerosoyl- [mycocerosate synthase] + 5 CoA + 4 CO(2) + 8 NADP(+) + 4 H(2)O.
|
3 | A0A139Y074 S8F5N9 V5BCV6 |
[Acyl-carrier-protein] S-malonyltransferase.
[EC: 2.3.1.39]
Malonyl-CoA + an [acyl-carrier-protein] = CoA + a malonyl-[acyl-carrier- protein].
|
2 | A0A0K3BVL1 U4EC35 |
Lovastatin nonaketide synthase.
[EC: 2.3.1.161]
9 malonyl-CoA + 11 NADPH + S-adenosyl-L-methionine + holo-[lovastatin nonaketide synthase] = dihydromonacolin L-[lovastatin nonaketide synthase] + 9 CoA + 9 CO(2) + 11 NADP(+) + S-adenosyl-L-homocysteine + 6 H(2)O.
|
1 | A0A0F8B1C0 |
3-oxoacyl-[acyl-carrier-protein] reductase.
[EC: 1.1.1.100]
(3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + NADPH.
|
1 | A0A0N1GUD6 |