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CATH Superfamily 3.40.47.10

Thiolase/Chalcone synthase

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 30385: Bisdemethoxycurcumin synthase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Bisdemethoxycurcumin synthase. [EC: 2.3.1.211]
2 4-coumaroyl-CoA + malonyl-CoA + H(2)O = 3 CoA + bisdemethoxycurcumin + 2 CO(2).
  • A polyketide synthase characterized from the plant Oryza sativa (rice) that catalyzes the formation of the C(6)-C(7)-C(6) diarylheptanoid scaffold of bisdemethoxycurcumin.
  • Unlike the process in the plant Curcuma longa (turmeric), where the conversion is carried out via a diketide intermediate by two different enzymes, the diketide intermediate formed by this enzyme remains within the enzyme's cavity and is not released to the environment.
  • Formerly EC 2.3.1.n9.
 2 Q8LIL0 Q8LIL0