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CATH Superfamily 3.40.420.10

Ricin (A subunit), domain 1

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Ricin (A subunit), domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 228: Ribosome-inactivating protein momordin I

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
RRNA N-glycosylase. [EC: 3.2.2.22]
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
  • Ricin A-chain and related toxins show this activity.
  • Naked rRNA is attacked more slowly than rRNA in intact ribosomes.
  • Naked rRNA from Escherichia coli is cleaved at a corresponding position.
 371 A0A061F5T3 A0A061F5V2 A0A061F6Q4 A0A061F765 A0A067KEZ0 A0A067LC40 A0A067LC46 A0A067LCC0 A0A067LML5 A0A067LNK5
(361 more...)