View in Gene3D

CATH Superfamily 3.40.390.10

Collagenase (Catalytic Domain)

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Collagenase (Catalytic Domain)
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 13260: Extracellular alkaline metalloprotease AprA

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Serralysin. [EC: 3.4.24.40]
Preferential cleavage of bonds with hydrophobic residues in P1'.
  • An extracellular endopeptidase from Pseudomonas aeruginosa, Escherichia freundii, Serratia marcescens and Erwinia chrysanthemi.
  • There is broad specificity in cleavage of the insulin B chain, with some species variations.
  • The pH optimum for digesting various proteins is about 9-10.
  • Belongs to peptidase family M10A.
  • Formerly EC 3.4.24.4.
 77 A0A067A6J3 A0A084YQL0 A0A0A8RNS4 A0A0B7D9S9 A0A0B7DBY3 A0A0D0RPU8 A0A0D6I7N5 A0A0F7A4C1 A0A0F7Y1N4 A0A0G3VN57
(67 more...)