The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Malonyl-Coenzyme A Acyl Carrier Protein, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12565: Polyketide synthase type I

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 7 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity GO:0004316
Catalysis of the reaction: (3R)-3-hydroxyacyl-
2 Q5AUX1 (/RCA) Q5BH30 (/RCA)
NADH dehydrogenase (ubiquinone) activity GO:0008137
Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol.
2 Q5AUX1 (/RCA) Q5BH30 (/RCA)
Complement binding GO:0001848
Interacting selectively and non-covalently with any component or product of the complement cascade.
1 Q4WZA8 (/IDA)
Catalytic activity GO:0003824
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
1 Q5LV53 (/ISS)
Transferase activity, transferring acyl groups other than amino-acyl groups GO:0016747
Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
1 Q9ZGI5 (/IDA)
Phosphopantetheine binding GO:0031177
Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).
1 Q9ZGI5 (/TAS)
Hydroquinone:oxygen oxidoreductase activity GO:0052716
Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.
1 Q03149 (/IMP)

There are 34 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Secondary metabolic process GO:0019748
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
17 A2QG45 (/NAS) A2QH36 (/NAS) A2QTE9 (/NAS) A2QTH2 (/NAS) A2QUI2 (/NAS) A2QX22 (/NAS) A2R3M8 (/NAS) Q03149 (/NAS) Q12397 (/NAS) Q4WA61 (/NAS)
(7 more)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
3 Q2UG06 (/IGC) Q4WA61 (/IGC) Q5BG07 (/IGC)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
3 Q4WA61 (/IMP) Q5BG07 (/IMP) Q5BH30 (/IMP)
Sterigmatocystin biosynthetic process GO:0045461
The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
3 Q12397 (/IMP) Q5AUX1 (/IMP) Q5BH30 (/IMP)
Pigment biosynthetic process GO:0046148
The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
3 Q03149 (/IMP) Q2UA48 (/IMP) Q4WZA8 (/IMP)
O-orsellinic acid biosynthetic process GO:1900584
The chemical reactions and pathways resulting in the formation of o-orsellinic acid.
3 Q12397 (/IMP) Q5AUX1 (/IMP) Q5BH30 (/IMP)
Monodictyphenone biosynthetic process GO:1900815
The chemical reactions and pathways resulting in the formation of monodictyphenone.
3 Q12397 (/IMP) Q5AUX1 (/IMP) Q5BH30 (/IMP)
Fatty acid biosynthetic process GO:0006633
The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
2 Q5AUX1 (/RCA) Q5BH30 (/RCA)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
2 Q2TXQ8 (/IGC) Q4KCY8 (/IGC)
Melanin biosynthetic process GO:0042438
The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
2 A2QUI2 (/IMP) Q4WZA8 (/IMP)
Pigment metabolic process involved in developmental pigmentation GO:0043324
The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.
2 A2QUI2 (/IMP) Q03149 (/IMP)
Emericellamide biosynthetic process GO:1900557
The chemical reactions and pathways resulting in the formation of emericellamide.
2 Q12397 (/IMP) Q5AUX1 (/IMP)
Unsaturated fatty acid biosynthetic process GO:0006636
The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
1 O65933 (/IMP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q4WZA8 (/IMP)
Nonribosomal peptide biosynthetic process GO:0019184
The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
1 Q5LV53 (/ISS)
Secondary metabolic process GO:0019748
The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
1 Q12397 (/RCA)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
1 Q4KCY8 (/IC)
Polyketide biosynthetic process GO:0030639
The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
1 Q2TXQ8 (/IEP)
Macrolide biosynthetic process GO:0033068
The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
1 Q9ZGI5 (/IDA)
Macrolide biosynthetic process GO:0033068
The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
1 Q9ZGI5 (/IMP)
Asperthecin biosynthetic process GO:0036184
The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
1 Q5B0D0 (/IMP)
Growth GO:0040007
The increase in size or mass of an entire organism, a part of an organism or a cell.
1 O65933 (/IMP)
Asexual spore wall assembly GO:0042243
The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.
1 Q4WZA8 (/IMP)
Secondary metabolite biosynthetic process GO:0044550
The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
1 Q5BG07 (/IEP)
Response to host GO:0075136
Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q4WZA8 (/IEP)
Emodin biosynthetic process GO:1900575
The chemical reactions and pathways resulting in the formation of emodin.
1 Q5BH30 (/IMP)
Arugosin biosynthetic process GO:1900587
The chemical reactions and pathways resulting in the formation of arugosin.
1 Q5BH30 (/IMP)
Violaceol I biosynthetic process GO:1900590
The chemical reactions and pathways resulting in the formation of violaceol I.
1 Q5AUX1 (/IMP)
Violaceol II biosynthetic process GO:1900593
The chemical reactions and pathways resulting in the formation of violaceol II.
1 Q5AUX1 (/IMP)
F-9775A biosynthetic process GO:1900611
The chemical reactions and pathways resulting in the formation of F-9775A.
1 Q5AUX1 (/IMP)
F-9775B biosynthetic process GO:1900614
The chemical reactions and pathways resulting in the formation of F-9775B.
1 Q5AUX1 (/IMP)
Naphtho-gamma-pyrone biosynthetic process GO:1900787
The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.
1 A2QUI2 (/IMP)
Shamixanthone biosynthetic process GO:1900793
The chemical reactions and pathways resulting in the formation of shamixanthone.
1 Q5BH30 (/IMP)
Monodictyphenone metabolic process GO:1900813
The chemical reactions and pathways involving monodictyphenone.
1 Q5BH30 (/IMP)

There are 0 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
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