View in Gene3D

CATH Superfamily 3.40.350.10

Creatinase/prolidase N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Creatinase/prolidase N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1129: Aminopeptidase P

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Xaa-Pro aminopeptidase. [EC: 3.4.11.9]
Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.
  • Generally membrane bound enzyme present in both mammalian and bacterial cells.
  • Belongs to peptidase family M24B.
 8 A0A0Y7J8Q6 A0A0Y7L589 A0A120SL44 A0A158SUW9 E1XBC0 F2C0A7 P44881 Q4QM84
Alanine--tRNA ligase. [EC: 6.1.1.7]
ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
    		 3 A0A0H3PJA3 A4N357 A4NX63
    Xaa-Pro dipeptidase. [EC: 3.4.13.9]
    Hydrolysis of Xaa-|-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-|-Pro.
    • Possibly thiol dependent.
    • Cytosolic from most animal tissues.
    • Belongs to peptidase family M24A.
    • Formerly EC 3.4.3.7.
    		 2 A0A120SL44 E1XBC0