The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17576: Aldehyde dehydrogenase family protein

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Benzaldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.28]
Benzaldehyde + NAD(+) + H(2)O = benzoate + NADH.
    23 A0A081G2S0 A0A0C5V8M4 A0A0F7A268 A0A0L8IRR5 A0A0N0F462 A0A0Q0C686 A0A193SRX6 A0A1C3JMG3 A0A1D3JZV3 A0A1E3XQW1
    (13 more...)
    Lactaldehyde dehydrogenase. [EC: 1.2.1.22]
    (S)-lactaldehyde + NAD(+) + H(2)O = (S)-lactate + NADH.
      1 F2LVP3
      Aldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.3]
      An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
      • Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
      • Formerly EC 1.1.1.70.
      1 Q0WSF1