The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17433: Probable aldehyde dehydrogenase YcbD

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Aldehyde dehydrogenase (NAD(P)(+)). [EC: 1.2.1.5]
An aldehyde + NAD(P)(+) + H(2)O = a carboxylate + NAD(P)H.
    5 A0A0K6JRL3 A0A0K6JVK0 A0A0K6KGU3 A0A0K6L0A4 A0A0T8PTA3
    Aldehyde dehydrogenase (NAD(+)). [EC: 1.2.1.3]
    An aldehyde + NAD(+) + H(2)O = a carboxylate + NADH.
    • Wide specificity, including oxidation of D-glucuronolactone to D-glucarate.
    • Formerly EC 1.1.1.70.
    5 A0A0M0KY47 A0A164W5L2 A0A1D8FUL9 G4NTN1 P42236
    Glyceraldehyde-3-phosphate dehydrogenase (NADP(+)). [EC: 1.2.1.9]
    D-glyceraldehyde 3-phosphate + NADP(+) + H(2)O = 3-phospho-D-glycerate + NADPH.
      1 A0A0T8PTA3
      2,5-dioxovalerate dehydrogenase. [EC: 1.2.1.26]
      2,5-dioxopentanoate + NADP(+) + H(2)O = 2-oxoglutarate + NADPH.
        1 M4KRA8
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