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CATH Superfamily 3.40.309.10

Aldehyde Dehydrogenase; Chain A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Aldehyde Dehydrogenase; Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 16644: Delta-1-pyrroline-5-carboxylate synthase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Glutamate-5-semialdehyde dehydrogenase. [EC: 1.2.1.41]
L-glutamate 5-semialdehyde + phosphate + NADP(+) = L-glutamyl 5-phosphate + NADPH.
    		 6 A0A061IBJ4 G3HXX8 K7D0Y1 P54886 Q5R4M8 Q9Z110
    Glutamate 5-kinase. [EC: 2.7.2.11]
    ATP + L-glutamate = ADP + L-glutamate 5-phosphate.
    • The product rapidly cyclizes to 5-oxoproline and phosphate.
    		 4 K7D0Y1 P54886 Q5R4M8 Q9Z110