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CATH Superfamily 3.40.30.10

Glutaredoxin

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Glutaredoxin
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 80100: Glutathione S-transferase kappa 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-hydroxychromene-2-carboxylate isomerase. [EC: 5.99.1.4]
2-hydroxy-2H-chromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut- 3-enoate.
  • This enzyme is involved in naphthalene degradation.
 68 A0A071KTF5 A0A071KTF5 A0A077JNZ7 A0A077JNZ7 A0A0B7DF65 A0A0B7DF65 A0A0D0RX65 A0A0D0RX65 A0A0E1AL31 A0A0E1AL31
(58 more...)
Glutathione transferase. [EC: 2.5.1.18]
RX + glutathione = HX + R-S-glutathione.
  • A group of enzymes of broad specificity.
  • R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
  • Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange.
  • Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.
 20 B6DYQ0 B6DYQ0 B7QC64 B7QC64 D7G2K7 D7G2K7 P24473 P24473 Q09652 Q09652
(10 more...)
Protein disulfide-isomerase. [EC: 5.3.4.1]
Catalyzes the rearrangement of -S-S- bonds in proteins.
  • Needs reducing agents or partly reduced enzyme; the reaction depends on sulfhydryl-disulfide interchange.
 12 A0A031JBP0 A0A031JBP0 A0A0G3XN71 A0A0G3XN71 A2TC28 A2TC28 C8CHQ4 C8CHQ4 G6EL40 G6EL40
(2 more...)
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