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CATH Superfamily 3.40.190.10

Periplasmic binding protein-like II

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Periplasmic binding protein-like II
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 82772: Putative amino-acid ABC transporter-binding protei...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
CTP synthase (glutamine hydrolyzing). [EC: 6.3.4.2]
ATP + UTP + L-glutamine = ADP + phosphate + CTP + L-glutamate.
  • The enzyme contains three functionally distinct sites: an allosteric GTP-binding site, a glutaminase site where glutamine hydrolysis occurs (cf. EC 3.5.1.2), and the active site where CTP synthesis takes place.
  • The reaction proceeds via phosphorylation of UTP by ATP to give an activated intermediate 4-phosphoryl UTP and ADP.
  • Ammonia then reacts with this intermediate generating CTP and a phosphate.
  • The enzyme can also use ammonia from the surrounding solution.
 8 A0A0E1SPX9 A0A0H3PF51 A0A112V103 A0A112VAV8 A4N217 A4NWJ6 A5UIK6 Q4QLK8
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