The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
MOFRL domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 607: Putative hydroxypyruvate reductase protein

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Hydroxypyruvate reductase. [EC: 1.1.1.81]
D-glycerate + NAD(P)(+) = hydroxypyruvate + NAD(P)H.
    370 A0A011NQH1 A0A011PER7 A0A011Q6X6 A0A021XAL6 A0A024HF82 A0A060HZT0 A0A060V616 A0A063BC61 A0A066PIH4 A0A066PU52
    (360 more...)
    Glycerate 3-kinase. [EC: 2.7.1.31]
    ATP + D-glycerate = ADP + 3-phospho-D-glycerate.
      22 A0A024R302 A0A066PIH4 C6BUX2 D5CSS9 E0SR62 E1JU16 F0J399 F7XMG6 G2SJG2 G8TCU3
      (12 more...)
      Glycerate 2-kinase. [EC: 2.7.1.165]
      ATP + D-glycerate = ADP + 2-phospho-D-glycerate.
      • A key enzyme in the nonphosphorylative Entner-Doudoroff pathway in archaea.
      • In Hyphomicrobium methylovorum GM2 the enzyme is involved in formaldehyde assaimilation I (serine pathway).
      • In Escherichia coli the enzyme is involved in D-glucarate/D-galactarate degradation.
      19 A0A0C7NX02 A0A0S1XB20 A0A1G4G646 I4BXB5 I4CEW7 J1IME5 K9F745 M7TUB8 N1JZ40 O58231
      (9 more...)
      Glycerate dehydrogenase. [EC: 1.1.1.29]
      D-glycerate + NAD(+) = hydroxypyruvate + NADH.
        18 A0A086IGD4 A0A0E1CFL5 A0A0H3GS22 A0A1C0UIA1 A0A1C0UM25 A0A1L3R1K0 A0A1L3RG90 A0A1L3RNH0 A0A1L3RVN3 A3RRN6
        (8 more...)
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