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CATH Superfamily 3.40.1410.10

Chorismate lyase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Chorismate lyase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4684: Probable chorismate pyruvate-lyase 1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Chorismate lyase. [EC: 4.1.3.40]
Chorismate = 4-hydroxybenzoate + pyruvate.
  • Catalyzes the first step in the biosynthesis of ubiquinone in Escherichia coli and other Gram-negative bacteria.
  • The yeast Saccharomyces cerevisiae can synthesize ubiquinone from either chorismate or tyrosine.
 2797 A0A009FUR5 A0A009G3K6 A0A009GKW8 A0A009H9H4 A0A009HSR9 A0A009JB07 A0A009KQF7 A0A009KWE8 A0A009MHD8 A0A009Q3H2
(2787 more...)
4-hydroxybenzoate polyprenyltransferase. [EC: 2.5.1.39]
A polyprenyl diphosphate + 4-hydroxybenzoate = diphosphate + a 4-hydroxy- 3-polyprenylbenzoate.
  • This enzyme, involved in the biosynthesis of ubiquinone, attaches a polyprenyl side chain to a 4-hydroxybenzoate ring, producing the first ubiquinone intermediate that is membrane bound.
  • The number of isoprenoid subunits in the side chain varies in different species.
  • The enzyme does not have any specificity concerning the length of the polyprenyl tail, and accepts tails of various lengths with similar efficiency.
 1 A0A0A2VXJ7
Hydroxymethylglutaryl-CoA lyase. [EC: 4.1.3.4]
(S)-3-hydroxy-3-methylglutaryl-CoA = acetyl-CoA + acetoacetate.
    		 1 A0A0P0UQD9