The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Cytidine Deaminase, domain 2
".
FunFam 12099: DNA dC->dU-editing enzyme APOBEC-3B
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 5 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Deoxycytidine deaminase activity GO:0047844
Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
|
2 | P31941 (/IMP) Q9UH17 (/IMP) |
|
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
|
1 | Q9UH17 (/IDA) |
|
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
|
1 | P31941 (/IDA) |
|
Cytidine deaminase activity GO:0004126
Catalysis of the reaction: cytidine + H2O = uridine + NH3.
|
1 | P31941 (/IMP) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P31941 (/IPI) |
There are 9 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Negative regulation of transposition GO:0010529
Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
|
2 | P31941 (/IDA) Q9UH17 (/IDA) |
|
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
|
2 | P31941 (/IDA) Q9UH17 (/IDA) |
|
Clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine GO:0044356
A defense process that protects an organism from invading foreign DNA. The process begins by the deamination of foreign double-stranded DNA cytidines to uridines. These atypical DNA nucleosides are then converted by a uracil DNA glycosylase to abasic lesions, and the process ends with the degradation of the foreign DNA.
|
1 | P31941 (/IDA) |
|
Negative regulation of viral genome replication GO:0045071
Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
|
1 | P31941 (/IDA) |
|
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
|
1 | P31941 (/IDA) |
|
DNA cytosine deamination GO:0070383
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
1 | P31941 (/IDA) |
|
DNA cytosine deamination GO:0070383
The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
|
1 | P31941 (/IMP) |
|
Cellular response to xenobiotic stimulus GO:0071466
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
|
1 | P31941 (/IDA) |
|
DNA demethylation GO:0080111
The removal of a methyl group from one or more nucleotides within an DNA molecule.
|
1 | P31941 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
3 | B0QYD3 (/IDA) P31941 (/IDA) Q9UH17 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | P31941 (/IDA) |
