View in Gene3D

CATH Superfamily 3.40.1160.10

Acetylglutamate kinase-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Acetylglutamate kinase-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 9204: Bifunctional aspartokinase/homoserine dehydrogenas...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Homoserine dehydrogenase. [EC: 1.1.1.3]
L-homoserine + NAD(P)(+) = L-aspartate 4-semialdehyde + NAD(P)H.
  • The enzyme from Saccharomyces cerevisiae acts most rapidly with NAD(+); the Neurospora enzyme with NADP(+).
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 2.7.2.4.
 114 A0A029IEB5 A0A029J372 A0A029JWV5 A0A062Y2V0 A0A068YUW5 A0A069XJV5 A0A070UWQ5 A0A073GEM5 A0A073GZM9 A0A073UI67
(104 more...)
Aspartate kinase. [EC: 2.7.2.4]
ATP + L-aspartate = ADP + 4-phospho-L-aspartate.
  • The enzyme from Escherichia coli is a multifunctional protein, which also catalyzes the reaction of EC 1.1.1.3.
  • This is also the case for two of the four isoenzymes in Arabidopsis thaliana.
  • The equilibrium constant strongly favors the reaction from right to left, i.e. the non-physiological direction of reaction.
 100 A0A068YUW5 A0A077N4J1 A0A077NHY2 A0A077NTW9 A0A077P9V4 A0A077PMH6 A0A077QGE7 A0A081RX57 A0A085GPT9 A0A085HGV6
(90 more...)
L-arabinitol 2-dehydrogenase. [EC: 1.1.1.13]
L-arabinitol + NAD(+) = L-ribulose + NADH.
    		 19 A0A0E1NQJ6 A0A0E8XK29 A0A0H2YFP4 A0A0M1VC05 A0A0T9JB18 A0A0T9LA63 A0A0T9LI40 A0A0T9M0T6 A0A0T9NP55 A0A0T9P3X5
    (9 more...)