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CATH Superfamily 3.40.1110.10

Calcium-transporting ATPase, cytoplasmic domain N

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic domain N
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15489: Calcium-transporting P-type ATPase, PMR1-type

There are 10 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Calcium-transporting ATPase. [EC: 3.6.3.8]
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae.
  • The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions.
  • Formerly EC 3.6.1.38.
 1234 A0A010RQE6 A0A011PP65 A0A011RK77 A0A015ND66 A0A016RXI2 A0A016RXT3 A0A022VZ29 A0A022XPY2 A0A023F4S7 A0A023P005
(1224 more...)
Hydrogen/potassium-exchanging ATPase. [EC: 3.6.3.10]
ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
  • Formerly EC 3.6.1.36.
 25 A0A081Q7T7 A0A0D5MJ53 A0A0F2DJB8 A0A0H2ZP05 A0A171JAC0 A0A1F0RYG6 A0A1M3UH15 A3CM87 A8AYN6 A8YUA7
(15 more...)
Cu(2+)-exporting ATPase. [EC: 3.6.3.4]
ATP + H(2)O + Cu(2+)(Side 1) = ADP + phosphate + Cu(2+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell.
 8 A0A090RTC8 A0A095XSZ9 A0A0U1L136 L8MFY9 M5DJR0 M5DPQ4 R1AS97 R1ASG3
Cadmium-exporting ATPase. [EC: 3.6.3.3]
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
 8 A0A090RTC8 A0A095XSZ9 A0A0U1L136 L8MFY9 M5DJR0 M5DPQ4 R1AS97 R1ASG3
Sodium/potassium-exchanging ATPase. [EC: 3.6.3.9]
ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
  • It is involved in generating the plasma membrane electrical potential.
  • Formerly EC 3.6.1.37.
 5 A0A062V8M2 A0A0E1PGB9 C0WZB9 C2FGU0 C2LQ69
Magnesium-importing ATPase. [EC: 3.6.3.2]
ATP + H(2)O + Mg(2+)(Out) = ADP + phosphate + Mg(2+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
 5 A9NGD8 F4BMX5 U4KQ61 W7NTE6 W7PLC8
Fe(3+)-transporting ATPase. [EC: 3.6.3.30]
ATP + H(2)O + Fe(3+)(Out) = ADP + phosphate + Fe(3+)(In).
  • A bacterial enzyme that imports ferric cations.
 1 F4BMX5
Manganese-transporting ATPase. [EC: 3.6.3.35]
ATP + H(2)O + Mn(2+)(Out) = ADP + phosphate + Mn(2+)(In).
  • A bacterial enzyme that imports Mn(2+), Zn(2+) and iron chelates.
 1 M9PG15
Zinc-exporting ATPase. [EC: 3.6.3.5]
ATP + H(2)O + Zn(2+)(In) = ADP + phosphate + Zn(2+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme also exports Cd(2+) and Co(2+).
 1 L8MFY9
Sodium-exporting ATPase. [EC: 3.6.3.7]
ATP + H(2)O + Na(+)(In) = ADP + phosphate + Na(+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Involved in the efflux of Na(+), with one ion being exported per ATP hydrolyzed.
 1 B9W6J0
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