The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic domain N
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15480: Sodium/potassium-transporting ATPase subunit alpha

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sodium/potassium-exchanging ATPase. [EC: 3.6.3.9]
ATP + H(2)O + Na(+)(In) + K(+)(Out) = ADP + phosphate + Na(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • An enzyme from the plasma membrane of animal cells that catalyzes the efflux of three Na(+) and influx of two K(+) per ATP hydrolyzed.
  • It is involved in generating the plasma membrane electrical potential.
  • Formerly EC 3.6.1.37.
158 A0A061HXE6 A0A061HXE6 A0A0A0V4P4 A0A0A0V4P4 A0A0B4MZT0 A0A0B4MZT0 A0A0C4L946 A0A0C4L946 A0A0C4UQR2 A0A0C4UQR2
(148 more...)
Hydrogen/potassium-exchanging ATPase. [EC: 3.6.3.10]
ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
  • Formerly EC 3.6.1.36.
28 A0A061HW93 A0A061HW93 P09626 P09626 P19156 P19156 P20648 P20648 P27112 P27112
(18 more...)
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    2 G5BWK8 G5BWK8
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