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CATH Superfamily 3.40.1110.10

Calcium-transporting ATPase, cytoplasmic domain N

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic domain N
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15447: Probable phospholipid-transporting ATPase IIA

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phospholipid-translocating ATPase. [EC: 3.6.3.1]
ATP + H(2)O + phospholipid(Side 1) = ADP + phosphate + phospholipid(Side 2).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme apparently has several activities, one of them being the movement of phospholipids from one membrane face to the other.
  • Formerly EC 3.6.3.13.
 806 A0A010RE21 A0A015JQG2 A0A016X3B9 A0A022VN85 A0A022XDX0 A0A023FKK8 A0A026W4M7 A0A044T6V8 A0A059J284 A0A059J2I9
(796 more...)
Very-long-chain 3-oxoacyl-CoA reductase. [EC: 1.1.1.330]
A very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH.
  • The second component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and stearoyl-CoA (and modified forms thereof) to very-long-chain acyl CoAs.
  • The enzyme is active with substrates with chain length of C(16) to C(34), depending on the species.
  • Cf. EC 2.3.1.199, EC 4.2.1.134 and EC 1.3.1.93.
  • Formerly EC 1.1.1.n13 and EC 2.3.1.119.
 1 A0A163IPU8
Calcium-transporting ATPase. [EC: 3.6.3.8]
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae.
  • The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions.
  • Formerly EC 3.6.1.38.
 1 A0A0U1CPP0
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