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CATH Superfamily 3.40.1110.10

Calcium-transporting ATPase, cytoplasmic domain N

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic domain N
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15425: Sodium P-type ATPase, putative

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Sodium-exporting ATPase. [EC: 3.6.3.7]
ATP + H(2)O + Na(+)(In) = ADP + phosphate + Na(+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Involved in the efflux of Na(+), with one ion being exported per ATP hydrolyzed.
 8 B0Y6D6 B0YD81 K0KJC4 P13587 Q01896 Q12691 Q4WD68 Q4WPJ1
Calcium-transporting ATPase. [EC: 3.6.3.8]
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum and in Saccharomyces cerevisiae.
  • The first and third transport one ion per ATP hydrolyzed, whereas the second transports two ions.
  • Formerly EC 3.6.1.38.
 1 P22189