The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Calcium-transporting ATPase, cytoplasmic domain N
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 15412: Copper-transporting P-type ATPase CopA

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Cu(2+)-exporting ATPase. [EC: 3.6.3.4]
ATP + H(2)O + Cu(2+)(Side 1) = ADP + phosphate + Cu(2+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • The enzyme from the termophilic bacterium Archaeoglobus fulgidus is involved in copper extrusion from the cell.
238 A0A017ILQ3 A0A023YSX2 A0A024KSD6 A0A025C9P6 A0A027TLA9 A0A028AHH8 A0A029IAK1 A0A029J1B2 A0A029L2Q5 A0A029LVI9
(228 more...)
Cu(+) exporting ATPase. [EC: 3.6.3.54]
ATP + H(2)O + Cu(+)(Side 1) = ADP + phosphate + Cu(+)(Side 2).
  • A P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • This enzyme transports Cu(+) or Ag(+), and cannot transport the divalent ions, contrary to EC 3.6.3.4, which mainly transports the divalent copper ion.
  • Formerly EC 3.6.3.n1.
48 A0A024KSD6 A0A037Y6P7 A0A070STB3 A0A0D6H8Q7 A0A0E0TVQ6 A0A0E1LW33 A0A0F6AXY1 A0A0F6C015 A0A0F6F236 A0A0F7J4D9
(38 more...)
Cadmium-exporting ATPase. [EC: 3.6.3.3]
ATP + H(2)O + Cd(2+)(In) = ADP + phosphate + Cd(2+)(Out).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
12 A0A023YSX2 A0A025C9P6 A0A0A1RD82 A0A0F3UGF0 A0A1C3PDE2 A0A1G4E159 E7SWB9 E7TBN8 G5RBS8 W1BG72
(2 more...)
Hydrogen/potassium-exchanging ATPase. [EC: 3.6.3.10]
ATP + H(2)O + H(+)(In) + K(+)(Out) = ADP + phosphate + H(+)(Out) + K(+)(In).
  • P-type ATPase that undergoes covalent phosphorylation during the transport cycle.
  • Hydrolysis of ATP is coupled with the exchange of H(+) and K(+) ions.
  • Formerly EC 3.6.1.36.
3 A0A0G2NJU7 A0A0K0H829 B5R622
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