The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
NADH Oxidase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 8447: Putative NADH dehydrogenase/NAD(P)H nitroreductase...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-hydroxypropionate dehydrogenase (NADP(+)). [EC: 1.1.1.298]
3-hydroxypropanoate + NADP(+) = 3-oxopropanoate + NADPH.
  • Catalyzes the reduction of 3-oxopropanoate to 3-hydroxypropanoate, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO(2) fixation pathways found in some green non-sulfur phototrophic bacteria and archaea, respectively.
  • The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyzes the upstream reaction in the pathway, EC 1.2.1.75.
  • Different from EC 1.1.1.59 by cofactor preference.
498 A0A014N2R1 A0A023YV75 A0A024KUU4 A0A024L557 A0A025C8C8 A0A026RS83 A0A026UWR8 A0A027U4V2 A0A028AW18 A0A028E1K2
(488 more...)