The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cobalt-precorrin-4 Transmethylase; Domain 1
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7136: Precorrin-6Y C(5,15)-methyltransferase [decarboxyl...

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Precorrin-6B C(5,15)-methyltransferase (decarboxylating). [EC: 2.1.1.132]
2 S-adenosyl-L-methionine + precorrin-6B = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO(2).
  • The enzyme, which participates in the aerobic adenosylcobalamin biosynthesis pathway, has S-adenosyl-L-methionine-dependent methyltransferase and decarboxylase activities.
  • The enzyme is a fusion protein with two active sites; one catalyzes the methylation at C(15) and the decarboxylation, while the other catalyzes the methylation at C(5).
13 A0A0A8RH27 A0A0F6UBX3 A0A0H2ZD02 A0A0H3R762 A0A0P1DAC9 A0A0U3SHK5 A0A157WTC3 A0A1D5C0Q0 A0A1E9CKW2 A0A1F0J6T9
(3 more...)