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CATH Superfamily 3.30.930.10

Bira Bifunctional Protein; Domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Bira Bifunctional Protein; Domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 31772: Amino acid--[acyl-carrier-protein] ligase 1

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Amino acid--[acyl-carrier-protein] ligase. [EC: 6.2.1.n2]
ATP + an amino acid + [acyl-carrier-protein] = AMP + diphosphate + an aminoacyl-[acyl-carrier-protein].
  • Catalyzes the ATP-dependent activation of L-alanine, and to a lesser extent of L-glycine and L-serine, and their transfer to the phosphopantetheine prosthetic group covalently attached to a vicinal carrier protein.
  • May participate in nonribosomal peptide synthesis or related processes.
  • L-proline and L-glutamate are very poor substrates whereas D-amino acids are not substrates for ATP-dependent activation.
  • Does not display tRNA aminoacylation activity.
 10 A0A021WWI6 A0A021WWI6 A0A1B3MC85 A0A1B3MC85 Q7CWR3 Q7CWR3 Q89GR3 Q89GR3 Q89VT8 Q89VT8
Serine--tRNA ligase. [EC: 6.1.1.11]
(1) ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser). (2) ATP + L-serine + tRNA(Sec) = AMP + diphosphate + L-seryl-tRNA(Sec).
  • This enzyme also recognizes tRNA(Sec), the special tRNA for selenocysteine, and catalyzes the formation of L-seryl-tRNA(Sec), the substrate for EC 2.9.1.1.
 6 Q2K2Z7 Q2K2Z7 Q6N112 Q6N112 W6RL72 W6RL72