The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
HORMA domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 584: HORMA domain-containing protein 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 1 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
2 Q5SQP1 (/IPI) Q9D5T7 (/IPI)

There are 19 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Meiotic sister chromatid cohesion GO:0051177
The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.
11 A2BF66 (/ISS) A6QQY4 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2QXH7 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
(1 more)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
11 A2BF66 (/ISS) A6QQY4 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2QXH7 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
(1 more)
Synaptonemal complex assembly GO:0007130
The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
8 A2BF66 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
8 A2BF66 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
Meiotic DNA double-strand break formation GO:0042138
The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.
8 A2BF66 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
8 A2BF66 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
Meiotic recombination checkpoint GO:0051598
A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.
8 A2BF66 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
Regulation of homologous chromosome segregation GO:0060629
Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
8 A2BF66 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
Blastocyst development GO:0001824
The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
6 D3ZWE7 (/ISS) E2IUK4 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q86X24 (/ISS)
Meiotic sister chromatid cohesion GO:0051177
The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.
2 Q5SQP1 (/IMP) Q9D5T7 (/IMP)
Meiotic cell cycle GO:0051321
Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
2 Q5SQP1 (/IEP) Q9D5T7 (/IEP)
Blastocyst development GO:0001824
The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
1 Q9D5T7 (/IMP)
Synapsis GO:0007129
The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Synapsis begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.
1 Q9D5T7 (/IMP)
Synaptonemal complex assembly GO:0007130
The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
1 Q9D5T7 (/IMP)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 Q9D5T7 (/IMP)
Meiotic DNA double-strand break formation GO:0042138
The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.
1 Q9D5T7 (/IMP)
Oogenesis GO:0048477
The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
1 Q9D5T7 (/IMP)
Meiotic recombination checkpoint GO:0051598
A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.
1 Q9D5T7 (/IMP)
Regulation of homologous chromosome segregation GO:0060629
Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
1 Q9D5T7 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
11 A2BF66 (/ISS) A6QQY4 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2QXH7 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q86X24 (/ISS)
(1 more)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 A2BF66 (/ISS) A6QQY4 (/ISS) D3ZWE7 (/ISS) E2IUK4 (/ISS) E2QXH7 (/ISS) E2RSQ2 (/ISS) Q2KIY6 (/ISS) Q4R8B9 (/ISS) Q5M7C8 (/ISS) Q8N7B1 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 Q5SQP1 (/IDA) Q86X24 (/IDA) Q9D5T7 (/IDA)
Synaptonemal complex GO:0000795
A proteinaceous scaffold found between homologous chromosomes during meiosis. It consists of 2 lateral elements and a central element, all running parallel to each other. Transverse filaments connect the lateral elements to the central element.
2 Q5SQP1 (/IDA) Q9D5T7 (/IDA)
Chromosome GO:0005694
A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
2 Q5SQP1 (/IDA) Q9D5T7 (/IDA)
Condensed nuclear chromosome GO:0000794
A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
1 Q9D5T7 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9D5T7 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9D5T7 (/IDA)