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CATH Superfamily 3.30.9.10

D-Amino Acid Oxidase, subunit A, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
D-Amino Acid Oxidase, subunit A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17883: Geranylgeranyl diphosphate reductase, chloroplasti...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2,3-bis-O-geranylgeranyl-sn-glycero-phospholipid reductase. [EC: 1.3.7.11]
A 2,3-bis-(O-phytanyl)-sn-glycero-phospholipid + 16 oxidized ferredoxin [iron-sulfur] cluster = a 2,3-bis-(O-geranylgeranyl)-sn-glycero- phospholipid + 16 reduced ferredoxin [iron-sulfur] cluster + 16 H(+).
  • The enzyme is involved in the biosynthesis of archaeal membrane lipids.
  • It catalyzes the reduction of all 8 double bonds in 2,3-bis-O- geranylgeranyl-sn-glycero-phospholipids and all 4 double bonds in 3-O-geranylgeranyl-sn-glycerol phospholipids with comparable activity.
  • Unlike EC 1.3.1.101, this enzyme shows no activity with NADPH, and requires a dedicated ferredoxin.
  • Formerly EC 1.3.99.34.
 133 A0A062UTD5 A0A063ZBY0 A0A075WA57 A0A076LF69 A0A099SZG4 A0A099T120 A0A0A7GDW2 A0A0E3KNT3 A0A0E3L147 A0A0E3L3M6
(123 more...)
2,3-bis-O-geranylgeranyl-sn-glycerol 1-phosphate reductase (NAD(P)H). [EC: 1.3.1.101]
2,3-bis-(O-phytanyl)-sn-glycerol 1-phosphate + 8 NAD(P)(+) = 2,3-bis- (O-geranylgeranyl)-sn-glycerol 1-phosphate + 8 NAD(P)H.
  • The enzyme from the archaeon Thermoplasma acidophilum is involved in the biosynthesis of membrane lipids.
  • In vivo the reaction occurs in the reverse direction with the formation of 2,3-bis-O-phytanyl-sn-glycerol 1-phosphate.
  • cf. EC 1.3.7.11.
 7 A0A151E1J3 A0A151EEC4 A0A151EIC1 A0A151EM79 M7TUU3 N6WT34 R9T7B0
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