The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Endonuclease Chain A
".
FunFam 12684: Chromosome 20 open reading frame 129
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 8 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q9H4H8 (/IPI) |
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | Q9H4H8 (/IDA) |
|
Microtubule binding GO:0008017
Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
|
1 | Q9D7I8 (/ISO) |
|
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
|
1 | Q9H4H8 (/IPI) |
|
Kinesin binding GO:0019894
Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
|
1 | Q9D7I8 (/ISO) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9H4H8 (/IPI) |
|
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
|
1 | Q9D7I8 (/ISO) |
There are 27 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
4 | A1L1G9 (/ISS) A3KN19 (/ISS) Q5XGY0 (/ISS) Q9D7I8 (/ISS) |
|
Metaphase plate congression GO:0051310
The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.
|
4 | A1L1G9 (/ISS) A3KN19 (/ISS) Q5XGY0 (/ISS) Q9D7I8 (/ISS) |
|
Regulation of ERK1 and ERK2 cascade GO:0070372
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
4 | A1L1G9 (/ISS) A3KN19 (/ISS) Q5XGY0 (/ISS) Q9D7I8 (/ISS) |
|
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Regulation of TOR signaling GO:0032006
Any process that modulates the frequency, rate or extent of TOR signaling.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Regulation of protein catabolic process GO:0042176
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Protein localization to mitotic spindle GO:1902480
A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition.
|
2 | A3KN19 (/ISS) Q9D7I8 (/ISS) |
|
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
1 | Q9H4H8 (/IDA) |
|
Epithelial to mesenchymal transition GO:0001837
A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
|
1 | Q9D7I8 (/ISO) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q9H4H8 (/IDA) |
|
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
|
1 | Q9D7I8 (/ISO) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | Q9H4H8 (/IDA) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | Q9D7I8 (/ISO) |
|
Regulation of TOR signaling GO:0032006
Any process that modulates the frequency, rate or extent of TOR signaling.
|
1 | Q9H4H8 (/IDA) |
|
Regulation of TOR signaling GO:0032006
Any process that modulates the frequency, rate or extent of TOR signaling.
|
1 | Q9D7I8 (/ISO) |
|
Regulation of protein catabolic process GO:0042176
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q9H4H8 (/IDA) |
|
Regulation of protein catabolic process GO:0042176
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
|
1 | Q9D7I8 (/ISO) |
|
Metaphase plate congression GO:0051310
The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.
|
1 | Q9H4H8 (/IMP) |
|
Metaphase plate congression GO:0051310
The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.
|
1 | Q9D7I8 (/ISO) |
|
Regulation of ERK1 and ERK2 cascade GO:0070372
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q9H4H8 (/IMP) |
|
Regulation of ERK1 and ERK2 cascade GO:0070372
Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q9D7I8 (/ISO) |
|
Protein localization to mitotic spindle GO:1902480
A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.
|
1 | Q9H4H8 (/IMP) |
|
Protein localization to mitotic spindle GO:1902480
A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.
|
1 | Q9D7I8 (/ISO) |
|
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition.
|
1 | Q9H4H8 (/IMP) |
|
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition.
|
1 | Q9D7I8 (/ISO) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
4 | A1L1G9 (/ISS) A3KN19 (/ISS) Q5XGY0 (/ISS) Q9D7I8 (/ISS) |
|
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
4 | A1L1G9 (/ISS) A3KN19 (/ISS) Q5XGY0 (/ISS) Q9D7I8 (/ISS) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9H4H8 (/IC) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9H4H8 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q9D7I8 (/ISO) |
|
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
1 | Q9H4H8 (/IDA) |
|
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
|
1 | Q9D7I8 (/ISO) |
