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CATH Superfamily 3.30.70.920

Lrp/AsnC effector binding domain/regulation of amino acid metabolism (RAM) domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 6291: Putative homocitrate synthase

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Homocitrate synthase. [EC: 2.3.3.14]
Acetyl-CoA + H(2)O + 2-oxoglutarate = (R)-2-hydroxybutane-1,2,4- tricarboxylate + CoA.
  • Belongs in the alpha-aminoadipate pathway of lysine synthesis, along with EC 4.2.1.36.
  • Also acts with oxaloacetate as substrate, but more slowly.
  • Formerly EC 4.1.3.21.
 10 A0A0E3JUD7 C3MPM7 C3MYM1 C3N5A3 C3NDV7 C3NHU6 C4KGW9 D0KTU9 Q971S5 Q97ZE0