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CATH Superfamily 3.30.70.270

Reverse transcriptase/Diguanylate cyclase domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 50464: Retrotransposon protein, putative, Ty3-gypsy subcl...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
RNA-directed DNA polymerase. [EC: 2.7.7.49]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes RNA-template-directed extension of the 3'-end of a DNA strand by one deoxynucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a RNA or DNA primer.
  • DNA can also serve as template.
  • See also EC 2.7.7.7.
 38 M5C202 M5C202 P03554 P03554 P03555 P03555 P03556 P03556 P04323 P04323
(28 more...)
Type II site-specific deoxyribonuclease. [EC: 3.1.21.4]
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates.
  • Large group of enzymes which recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition site.
  • See the REBASE database for a complete list of these enzymes: http://rebase.neb.com/rebase/
 28 H8ZVL2 H8ZVL2 H8ZVL3 H8ZVL3 H8ZVL4 H8ZVL4 H8ZVL5 H8ZVL5 H8ZVL6 H8ZVL6
(18 more...)
Ribonuclease H. [EC: 3.1.26.4]
Endonucleolytic cleavage to 5'-phosphomonoester.
  • Acts on RNA-DNA hybrids.
 12 M5C588 M5C588 P19199 P19199 P27502 P27502 Q7LHG5 Q7LHG5 Q89703 Q89703
(2 more...)
DNA-directed DNA polymerase. [EC: 2.7.7.7]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
 4 Q7LHG5 Q7LHG5 Q99315 Q99315