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CATH Superfamily 3.30.70.260

ACT domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 8707: (P)ppGpp synthetase, RelA/SpoT family

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Guanosine-3',5'-bis(diphosphate) 3'-diphosphatase. [EC: 3.1.7.2]
Guanosine 3',5'-bis(diphosphate) + H(2)O = guanosine 5'-diphosphate + diphosphate.
    		 105 A0A024HQK4 A0A061D6T9 A0A069Q2V6 A0A086BUD9 A0A098FXE7 A0A0A1I1D0 A0A0A4HN17 A0A0A6DIY8 A0A0C1WP53 A0A0D0TJY8
    (95 more...)
    GTP diphosphokinase. [EC: 2.7.6.5]
    ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
    • GDP can also act as acceptor.
    		 67 A0A031GB24 A0A031J862 A0A069Q2V6 A0A086BUD9 A0A098FXE7 A0A0A1I1D0 A0A0A4HN17 A0A0D0TJY8 A0A0D6T191 A0A0E1B748
    (57 more...)
    Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent). [EC: 5.4.2.2]
    Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
    • Maximum activity is only obtained in the presence of alpha-D-glucose 1,6-bisphosphate.
    • This bisphosphate is an intermediate in the reaction, being formed by transfer of a phosphate residue from the enzyme to the substrate, but the dissociation of bisphosphate from the enzyme complex is much slower than the overall isomerization.
    • Also, more slowly, catalyzes the interconversion of 1-phosphate and 6-phosphate isomers of many other alpha-D-hexoses, and the interconversion of alpha-D-ribose 1-phosphate and 5-phosphate.
    • Cf. EC 5.4.2.5.
    • Formerly EC 2.7.5.1.
    		 6 A0A0F4XKE5 A0A1H0WWX6 F2K6Y2 G8Q6Z0 I4JYU2 S6JSK2