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CATH Superfamily 3.30.70.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39769: Heterodisulfide reductase, subunit A

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
CoB--CoM heterodisulfide reductase. [EC: 1.8.98.1]
Coenzyme B + coenzyme M + methanophenazine = N-(7-((2-sulfoethyl)dithio)heptanoyl)-O(3)-phospho-L-threonine + dihydromethanophenazine.
  • Found in methanogenic archaea, particularly Methanosarcina species, and regenerates coenzyme M and coenzyme B after the action of EC 2.8.4.1.
  • Highly specific for both coenzyme M and coenzyme B.
  • Reacts with various phenazine derivatives, including 2-hydroxyphenazine and 2-bromophenazine.
  • Formerly EC 1.12.99.2.
 24 A0A090I3G7 A0A0E3LS50 A0A0E3RJL6 A0A0E3RRF5 A0A0E3S262 A0A101HAP1 A0A1D2WUE0 A0A1D3L596 A0A1F2P5N9 A0A1M4MUM9
(14 more...)
NADH dehydrogenase (quinone). [EC: 1.6.5.11]
NADH + a quinone = NAD(+) + a quinol.
  • Menaquinone or other quinones can act as acceptor.
  • Inhibited by AMP and 2,4-dinitrophenol but not by dicoumarol or folic acid derivatives.
  • Formerly EC 1.6.99.5.
 2 A0A166A7D7 A0A166AF71
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