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CATH Superfamily 3.30.70.20

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 39748: Formate dehydrogenase beta subunit

There are 7 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Formate dehydrogenase. [EC: 1.2.1.2]
Formate + NAD(+) = CO(2) + NADH.
  • The enzyme from most aerobic organisms is devoid of redox-active centers but that from the proteobacterium Methylosinus trichosporium contains iron-sulfur centers, flavin and a molybdenum center.
  • Together with EC 1.12.1.2, forms a system previously known as formate hydrogenlyase.
 1964 A0A017I2J8 A0A017I2J8 A0A017II69 A0A017II69 A0A023V6K6 A0A023V6K6 A0A023YWW0 A0A023YWW0 A0A023Z5H0 A0A023Z5H0
(1954 more...)
Glycolaldehyde dehydrogenase. [EC: 1.2.1.21]
Glycolaldehyde + NAD(+) + H(2)O = glycolate + NADH.
    		 192 A0A0D6G2X9 A0A0D6G2X9 A0A0E1NIP6 A0A0E1NIP6 A0A0F5BE98 A0A0F5BE98 A0A0F6B1I2 A0A0F6B1I2 A0A0F6B9K6 A0A0F6B9K6
    (182 more...)
    Formate dehydrogenase (cytochrome). [EC: 1.2.2.1]
    Formate + 2 ferricytochrome b1 = CO(2) + 2 ferrocytochrome b1 + 2 H(+).
      		 104 A0A060V0Y0 A0A060V0Y0 A0A066SRA7 A0A066SRA7 A0A066T5A6 A0A066T5A6 A0A087FN36 A0A087FN36 A0A090NEI1 A0A090NEI1
      (94 more...)
      Thiamine pyridinylase. [EC: 2.5.1.2]
      Thiamine + pyridine = 1-((4-amino-2-methylpyrimidin-5- yl)methyl)pyridinium + 4-methyl-5-(2-hydroxyethyl)thiazole.
      • Various bases and thiol compounds can act instead of pyridine.
      		 4 C4WLM3 C4WLM3 M5JUR6 M5JUR6
      Nitrate reductase. [EC: 1.7.99.4]
      Nitrite + acceptor = nitrate + reduced acceptor.
      • The Pseudomonas enzyme is a cytochrome, but the enzyme from Micrococcus halodenitrificans is an iron protein containing molybdenum.
      • Reduced benzyl viologen and other dyes bring about the reduction of nitrate.
      		 2 Q1IFP6 Q1IFP6
      Formate dehydrogenase-N. [EC: 1.1.5.6]
      Formate + a quinone = CO(2) + a quinol.
      • Formate dehydrogenase-N oxidizes formate in the periplasm, transferring electrons via the menaquinone pool in the cytoplasmic membrane to a dissimilatory nitrate reductase (EC 1.7.5.1), which transfers electrons to nitrate in the cytoplasm.
      • The system generates proton motive force under anaerobic conditions.
      		 2 Q8EKJ0 Q8EKJ0
      Formate dehydrogenase (NADP(+)). [EC: 1.2.1.43]
      Formate + NADP(+) = CO(2) + NADPH.
        		 2 S0G782 S0G782
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