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CATH Superfamily 3.30.70.1230

Nucleotide cyclase, GGDEF domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleotide cyclase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 4554: Ph-sensitive adenylate cyclase

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenylate cyclase. [EC: 4.6.1.1]
ATP = 3',5'-cyclic AMP + diphosphate.
  • Also acts on dATP to form 3',5'-cyclic dAMP.
  • Requires pyruvate.
  • Activated by NAD(+) in presence of EC 2.4.2.31.
 40 A0A045J282 A0A045J282 A0A083WAU6 A0A083WAU6 A0A0G4DXE6 A0A0G4DXE6 A0A0H3L7X4 A0A0H3L7X4 A0A0H3M4F1 A0A0H3M4F1
(30 more...)
Glycolate dehydrogenase. [EC: 1.1.99.14]
Glycolate + acceptor = glyoxylate + reduced acceptor.
  • Also acts on (R)-lactate.
  • 2,6-dichloroindophenol and phenazine methosulfate can act as acceptors.
 4 A0A0H3L7X4 A0A0H3L7X4 A0A1L7MGE0 A0A1L7MGE0