The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Nucleotide cyclase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2221: Adenylyl cyclase Cya

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Adenylate cyclase. [EC: 4.6.1.1]
ATP = 3',5'-cyclic AMP + diphosphate.
  • Also acts on dATP to form 3',5'-cyclic dAMP.
  • Requires pyruvate.
  • Activated by NAD(+) in presence of EC 2.4.2.31.
28 A0A0E8UFC7 A0A0G4E0J4 A0A0H3LDA5 A0A0H3M6I3 A0A0K2HVM7 A0A0T9B3S3 A0A0T9B705 A0A0T9BTB9 A0A0T9EP93 A0A0T9XA29
(18 more...)