The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ACT-like. Chain A, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 281: Acetolactate synthase, small subunit

There are 1 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Acetolactate synthase. [EC: 2.2.1.6]
2 pyruvate = 2-acetolactate + CO(2).
  • The reaction shown is in the pathway of biosynthesis of valine.
  • The enzyme can also transfer the acetaldehyde from pyruvate to 2-oxobutanoate, forming 2-ethyl-2-hydroxy-3-oxobutanoate, also known as 2-aceto-2-hydroxybutanoate, a reaction in the biosynthesis of isoleucine.
  • Formerly EC 4.1.3.18.
19 A0A0D0ING1 A0A0E1SML1 A0A0E1WLB7 A0A0H3PF08 A0A0K9L4I5 A0A0M3G2P9 A0A0Y0CKW9 A4MV22 A4N4F4 A5UJ39
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